Almost all sufferers of panic attacks report a fear of dying, "going crazy", having a heart attack, fainting, vomiting, or losing control of emotions or behavior. These feelings generally provoke a strong urge to escape or flee the place where the attack began ("fight or flight" reaction) and, when associated with chest pain or shortness of breath frequently result in the sufferer seeking medical attention, often in an emergency room. Panic attacks have been linked to high quantities of acetylcholinesterase in the blood. Also the release of adreno-cortisols aid in catalyzing the panic attacks.